Barry Olafson, Ph.D. – Chief Executive Officer and Co-Founder
Dr. Olafson received his Ph.D. from the California Institute of Technology in the laboratory of William A. Goddard III and completed his postdoctoral training with Martin Karplus at Harvard University. He was the CEO and co-founder of Molecular Simulations Inc. (MSI) along with Professors Goddard and Stephen Mayo. MSI later evolved into Accelrys (NASDAQ: ACCL). While at Harvard, he was involved in the initial design and implementation of CHARMM, and while at MSI, he co-authored the BIOGRAF molecular modeling program. Dr. Olafson continues to be involved in developing the DREIDING molecular mechanics forcefield and in applying it to biological systems.
Benjamin Allen, Ph.D. – Chief Technology Officer and Co-Founder
Dr. Allen received his Ph.D. from the California Institute of Technology in the laboratory of Stephen Mayo. He was the primary developer of the protein design program PHOENIX and created more efficient and broadly applicable algorithms for protein engineering. These include an improved version of the optimization algorithm FASTER, an efficient algorithm for multistate protein design, and methods for the design of combinatorial gene libraries for facile experimental screening or selection. These methods have been tested experimentally, have proven useful in several protein design projects, and have been integrated into Triad, Protabit’s software platform. Dr. Allen continues to lead the Protabit software development team in improving and adding new capabilities to Triad. Recent developments include advanced tools for homology modeling, loop design, inclusion of multiple sequence alignment data, and incorporation of experimental assay data directly into the protein design process.